Maria Giovanna Chini Selected Research

Cholestasis

1/2012

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.

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Maria Giovanna Chini Research Topics

Disease

10	Inflammation (Inflammations) 05/2024 - 11/2009
9	Neoplasms (Cancer) 05/2024 - 05/2009
3	Pain (Aches) 06/2020 - 03/2011
3	Rheumatoid Arthritis 10/2012 - 11/2009
3	Asthma (Bronchial Asthma) 10/2012 - 11/2009
3	Septic Shock (Toxic Shock Syndrome) 10/2012 - 11/2009
3	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2012 - 11/2009
2	Peritonitis 11/2021 - 07/2019
2	Hyperalgesia 07/2019 - 01/2017
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2018 - 01/2015
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2023
1	Leukemia 10/2023
1	Carcinoma (Carcinomatosis) 06/2023
1	T-Cell Lymphoma (Lymphoma, T Cell) 06/2023
1	Sepsis (Septicemia) 01/2022
1	COVID-19 11/2020
1	Triple Negative Breast Neoplasms 09/2020
1	Edema (Dropsy) 07/2019
1	Alzheimer Disease (Alzheimer's Disease) 01/2018
1	Gliosis 01/2018
1	Dementia (Dementias) 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2015
1	Seizures (Absence Seizure) 09/2013
1	Liver Diseases (Liver Disease) 01/2012
1	Necrosis 01/2012
1	Cholestasis 01/2012
1	Fever (Fevers) 03/2011
1	Crohn Disease (Crohn's Disease) 01/2011
1	Colitis 01/2011

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 05/2024 - 11/2020
3	Histone Deacetylase InhibitorsIBA 10/2023 - 05/2009
2	DiterpenesIBA 06/2023 - 01/2015
2	ZymosanIBA 11/2021 - 07/2019
2	Analgesics (Analgesic Drugs)IBA 06/2020 - 01/2017
2	Formaldehyde (Formol)FDA Link 07/2019 - 01/2017
2	cryptotanshinoneIBA 01/2018 - 01/2015
2	tanshinoneIBA 01/2018 - 01/2015
2	Secretory Phospholipases A2IBA 10/2012 - 11/2009
2	Phospholipases AIBA 10/2012 - 11/2011
2	LigandsIBA 01/2012 - 01/2011
2	Bile Acids and Salts (Bile Acids)IBA 01/2012 - 01/2011
1	Epoxide HydrolasesIBA 05/2024
1	Indicators and Reagents (Reagents)IBA 10/2023
1	Histones (Histone)IBA 10/2023
1	TubulinIBA 10/2023
1	oridoninIBA 06/2023
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 06/2023
1	LipopolysaccharidesIBA 01/2022
1	carnosolIBA 01/2022
1	loganic acidIBA 10/2021
1	gentiopicrosideIBA 10/2021
1	secalonic acidIBA 09/2020
1	Ammonium CompoundsIBA 07/2019
1	EnzymesIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	CarrageenanIBA 01/2017
1	CurcuminIBA 12/2015
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 09/2015
1	Cocaine (Cocaine HCl)IBA 09/2013
1	Protein Isoforms (Isoforms)IBA 07/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 07/2013
1	Antineoplastic Agents (Antineoplastics)IBA 07/2013
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2012
1	7-hydroxytheonellasterolIBA 01/2012
1	Adenosine Triphosphate (ATP)IBA 01/2012
1	Alanine (L-Alanine)FDA Link 01/2012
1	SterolsIBA 01/2012
1	Prostaglandins EIBA 03/2011
1	ProstaglandinsIBA 03/2011
1	Prostaglandin H2 (PGH(2))IBA 03/2011
1	zonulinIBA 01/2011
1	Oleanolic AcidIBA 01/2011
1	Messenger RNA (mRNA)IBA 01/2011
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2011

Therapy/Procedure

3	Chinese Traditional Medicine (Traditional Chinese Medicine) 06/2020 - 01/2015
3	Therapeutics 07/2013 - 01/2012
1	Intraperitoneal Injections 07/2019
1	Ligation 01/2012